Description

[3-[(2,2-Dimethylpropylidene)Amino]Propyl]Phosphonic Acid Bis(Trimethylsilyl) Ester is a specialized organophosphorus compound featuring a protected phosphonic acid group and a sterically hindered imine functionality. This unique structure makes it a valuable protected intermediate and ligand precursor in advanced synthetic chemistry. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those requiring phosphonate or phosphate bioisosteres.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators that incorporate phosphonic acid derivatives.
• Ligand for Catalysis: Acts as a precursor for chelating ligands in transition metal catalysis, useful in cross-coupling and other organic transformations.
• Surface Modification Agent: Employed to functionalize metal oxides and other surfaces, imparting specific chemical properties for advanced material applications.
• Polymer Additive: Can be incorporated into polymer matrices as a flame retardant or stabilizer precursor.
• Organic Synthesis Reagent: Provides a masked phosphonic acid group for stepwise synthesis, allowing for selective deprotection under mild conditions.

Basic Information

Item	Details
Product Name	[3-[(2,2-Dimethylpropylidene)Amino]Propyl]Phosphonic Acid Bis(Trimethylsilyl) Ester
CAS No.	55108-79-7
Molecular Formula	C14H34NO3PSi2
Molecular Weight	351.57 g/mol
Synonyms	Bis(trimethylsilyl) [3-[(2,2-dimethylpropylidene)amino]propyl]phosphonate; (3-((2,2-Dimethylpropylidene)amino)propyl)phosphonic Acid Bis(trimethylsilyl) Ester; Phosphonic Acid, P-[3-[(2,2-dimethylpropylidene)amino]propyl]-, Bis(trimethylsilyl) Ester; TMS-Protected Neopentylideneaminopropylphosphonate; N-(3-(Bis(trimethylsilyloxy)phosphinyl)propyl)-2,2-dimethylpropylidenimine
EINECS	Contact for details

Quality Control

Our production of [3-[(2,2-Dimethylpropylidene)Amino]Propyl]Phosphonic Acid Bis(Trimethylsilyl) Ester adheres to stringent internal quality protocols. Every batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C, ³¹P), HPLC, and GC analysis, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis of the silyl ester groups. Keep away from strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.