Description

[1-[(2,2-Dimethylpropylidene)Amino]Pentyl]Phosphonic Acid Bis(Trimethylsilyl) Ester is a specialized organophosphorus compound featuring a silyl-protected phosphonic acid group and an imine functional group. This unique bifunctional structure makes it a valuable advanced synthetic intermediate and ligand precursor in sophisticated chemical synthesis. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures, including novel catalysts and bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring phosphonate or phosphate ester moieties.
• Agrochemical Synthesis: Used in the research and development of new herbicides, insecticides, and plant growth regulators that incorporate phosphonic acid derivatives.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Organometallic Chemistry: Employed in the preparation of metal complexes for catalytic applications and material science research.
• Peptide Mimetics & Prodrug Design: The protected phosphonate group is useful in designing peptide analogs and prodrug strategies to enhance bioavailability.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme mechanisms, particularly those involving phosphorylation.
• Advanced Material Precursor: Acts as a monomer or modifying agent in the development of specialty polymers and surface coatings.

Basic Information

Item	Detail
Product Name	[1-[(2,2-Dimethylpropylidene)Amino]Pentyl]Phosphonic Acid Bis(Trimethylsilyl) Ester
CAS No.	55108-76-4
Molecular Formula	C16H38NO3PSi2
Molecular Weight	379.62 g/mol
Synonyms	Bis(trimethylsilyl) [1-[(2,2-dimethylpropylidene)amino]pentyl]phosphonate; (1-[(2,2-Dimethylpropylidene)amino]pentyl)phosphonic Acid Bis(trimethylsilyl) Ester; Pivalideneaminoamylphosphonic Acid Bis(TMS) Ester; 1-(Neopentylideneamino)pentylphosphonic Acid Bis(trimethylsilyl) Ester; TMS-Protected Phosphonate Ester; Amino Phosphonate Silyl Ester; CAS 55108-76-4
EINECS	Contact for details

Quality Control

Our [1-[(2,2-Dimethylpropylidene)Amino]Pentyl]Phosphonic Acid Bis(Trimethylsilyl) Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and relevant physical data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.