Description

3β-(Acetyloxy)Pregn-5-Ene-20-Carbonyl Chloride is a high-purity steroid derivative and a key reactive intermediate in organic synthesis. Its primary commercial value lies in its role as a versatile building block for the preparation of more complex steroid-based pharmaceuticals and fine chemicals. This compound is essential for research and development laboratories and production facilities in the pharmaceutical, biotechnology, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of steroidal drugs, including hormone modulators and anti-inflammatory agents.
• Research & Development: Used in academic and industrial R&D for exploring new synthetic pathways and creating novel steroid analogs.
• Fine Chemical Synthesis: Serves as a precursor in the multi-step synthesis of complex organic molecules for specialized applications.
• Bioconjugation: The reactive carbonyl chloride group enables its use in conjugation chemistry for creating labeled compounds or prodrugs.

Basic Information

Product Name	3β-(Acetyloxy)Pregn-5-Ene-20-Carbonyl Chloride
CAS No.	55103-88-3
Molecular Formula	C24H33ClO3
Molecular Weight	404.97 g/mol
Synonyms	Pregnenolone Acetate 20-Carbonyl Chloride; 20-Chloro-20-oxo-3β-acetoxypregn-5-ene; 3β-Acetoxypregn-5-en-20-oyl Chloride; 3β-Hydroxypregn-5-en-20-one Acetate Chloride; 20-Carbonyl Chloride Pregnenolone Acetate; 5-Pregnen-3β-ol-20-one, acetate, 20-carbonyl chloride; (3β)-3-(Acetyloxy)pregn-5-en-20-oyl chloride
EINECS	Contact for details

Quality Control

Our 3β-(Acetyloxy)Pregn-5-Ene-20-Carbonyl Chloride is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality systems are designed to support cGMP-compliant applications where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.