Description

5,6-Didehydro-3,6-Dimethoxy-17-Methylmorphinan-7-One is a high-purity synthetic intermediate of significant importance in advanced pharmaceutical research and development. This compound serves as a critical precursor in the synthesis of complex active pharmaceutical ingredients (APIs), particularly within the opioid analgesic class. It is essential for pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in the development of new therapeutic agents and analytical reference standards.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potent analgesic APIs and related pharmacologically active compounds.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development, validation, and quality control testing of pharmaceutical products.
• Research & Development: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and the discovery of new chemical entities with targeted receptor activity.
• Metabolite Synthesis: Utilized in the synthesis of drug metabolites for pharmacokinetic and toxicological studies during drug development.
• Process Chemistry: Serves as a starting material or intermediate in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.

Basic Information

Product Name	5,6-Didehydro-3,6-Dimethoxy-17-Methylmorphinan-7-One
CAS No.	55101-91-2
Molecular Formula	C19H23NO3
Molecular Weight	313.39 g/mol
Synonyms	7,8-Didehydro-4,5α-epoxy-3,6α-dimethoxy-17-methylmorphinan-6-one; 6-O-Methyl-6-deoxy-6,14-ethenomorphine; 3,6-Dimethoxy-17-methyl-5,6-didehydromorphinan-7-one; 6-O-Methyl-6-deoxy-6,14-ethenooripavine; 5,6-Didehydro-3,6-dimethoxy-17-methylmorphinan-7-one; 6-O-Methyl-6-deoxy-6,14-ethenomorphinan-7-one
EINECS	Contact for details

Quality Control

Our 5,6-Didehydro-3,6-Dimethoxy-17-Methylmorphinan-7-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to confirm identity, potency, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.