Description

Butamirate Citrate is a pharmaceutical active ingredient primarily used as a non-opioid antitussive agent. This compound matters for its effectiveness in suppressing the cough reflex by acting on the central nervous system, offering a critical therapeutic option for managing persistent coughs. It is needed by pharmaceutical manufacturers and research institutions developing cough syrups, lozenges, and other respiratory formulations, ensuring reliable and high-purity supply for global healthcare markets.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the key therapeutic component in antitussive (cough suppressant) medications.
• Cough Syrup Formulations: Integration into liquid oral dosage forms for effective cough relief.
• Lozenges and Pastilles: Used in solid oral preparations designed for slow dissolution and localized throat relief.
• Pediatric Cough Remedies: Formulated in age-appropriate dosages for safe and effective use in children's medicines.
• Combination Drug Therapies: Combined with other APIs like expectorants or antihistamines in multi-symptom cold and flu preparations.
• Veterinary Pharmaceuticals: Application in medicinal products for treating respiratory conditions in animals.
• Clinical Research: Serves as a reference standard or investigational compound in pharmacological studies.
• Generic Drug Manufacturing: Sourcing for the production of cost-effective generic versions of branded antitussive drugs.

Basic Information

Product Name	Butamirate Citrate
CAS No.	18109-81-4
Molecular Formula	C18H29NO3 • C6H8O7
Molecular Weight	491.54 g/mol
Synonyms	2-(2-Diethylaminoethoxy)ethyl 2-phenylbutyrate citrate; Butamyrate Citrate; Butamirate Citrate Salt; Acobutamol Citrate; Sinecod (brand name); Butamirati Citras; Butamiratum; Butamirate hydrogen citrate
EINECS	Contact for details

Quality Control

Our Butamirate Citrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) are provided, detailing parameters such as assay, related substances, and residual solvents. We support compliance with major pharmacopoeial standards, including USP and EP, upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any individual impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.