Description

1-(5-Deoxy-β-D-Hexofuranosyl)Cytosine is a modified nucleoside derivative of cytidine, where the 5'-hydroxyl group of the ribose sugar is replaced by a hydrogen atom. This structural modification makes it a valuable intermediate in the synthesis of novel nucleoside analogs and prodrugs for pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in antiviral, anticancer, and other therapeutic discovery programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used in studies of nucleoside metabolism, enzyme inhibition, and as a substrate analog in enzymatic assays.
• Prodrug Development: Serves as a precursor molecule in the design of prodrugs aimed at improving drug delivery and bioavailability.
• Antiviral Agent Synthesis: A critical starting material in the research and development pipeline for new antiviral compounds.
• Labeled Compound Synthesis: Can be used to prepare isotopically labeled versions for pharmacokinetic and metabolic tracing studies.

Basic Information

Product Name	1-(5-Deoxy-β-D-Hexofuranosyl)Cytosine
CAS No.	55085-34-2
Molecular Formula	C10H15N3O4
Molecular Weight	241.24 g/mol
Synonyms	5'-Deoxycytidine; 1-(5-Deoxy-β-D-ribofuranosyl)cytosine; Cytidine, 5'-deoxy-; 5'-Deoxycytidine (VAN); β-5'-Deoxycytidine; 5'-dCyd; 5'-Deoxy-β-D-ribofuranosyl cytosine
EINECS	Contact for details

Quality Control

Our 1-(5-Deoxy-β-D-Hexofuranosyl)Cytosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, and custom synthesis to meet specific purity or packaging requirements is available.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.