Description

5'-Deoxy-5'-Thioadenosine 5'-Monophosphate is a modified nucleotide monophosphate derivative of adenosine, where the 5'-oxygen is replaced by a sulfur atom. This structural modification makes it a valuable biochemical tool and a key intermediate in the study of enzyme mechanisms, particularly those involving sulfur transfer and nucleotide metabolism. It is primarily utilized by research institutions and pharmaceutical companies engaged in biochemical research, enzymology, and the development of novel therapeutic agents.

Application

• Biochemical Research: Serves as a critical substrate or inhibitor in enzymatic studies, particularly for sulfurtransferases, methyltransferases, and kinases.
• Pharmaceutical R&D: Used as a building block or reference standard in the development of nucleotide-based drugs and prodrugs.
• Enzymology Studies: Employed to investigate reaction mechanisms involving adenosyl and thioadenosyl compounds.
• Metabolic Pathway Analysis: Acts as a probe or intermediate to study pathways like polyamine synthesis and methionine salvage.
• Diagnostic Reagent Development: Potential use in formulating assay kits for specific enzyme activity measurements.
• Academic Research: A key reagent for universities and labs focusing on nucleotide chemistry and molecular biology.

Basic Information

Product Name	5'-Deoxy-5'-Thioadenosine 5'-Monophosphate
CAS No.	55036-25-4
Molecular Formula	C11H16N5O6PS
Molecular Weight	401.32 g/mol
Synonyms	5'-Thioadenosine 5'-monophosphate; 5'-S-Deoxy-5'-thioadenosine monophosphate; 5'-Deoxy-5'-thioadenylic acid; 5'-Thio-5'-deoxyadenosine monophosphate; 5'-Thio-AMP; TAD; 5'-S-Methyl-5'-thioadenosine monophosphate (related); Adenosine-5'-(methylthio)phosphate
EINECS	Contact for details

Quality Control

Our 5'-Deoxy-5'-Thioadenosine 5'-Monophosphate is produced under a rigorous quality management system. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.