Description

(20β,25R)-5α-Spirostan-3-One CAS NO 55028-78-9 is a high-purity, specific stereoisomer of a spirostanone derivative, a key intermediate in the synthesis of bioactive steroids and sapogenins. Its defined stereochemistry is critical for ensuring the efficacy and specificity of downstream pharmaceutical and research compounds. This product is essential for manufacturers and research institutions engaged in the development of steroid-based APIs, reference standards, and novel chemical entities for therapeutic applications.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of steroidal active pharmaceutical ingredients (APIs) and hormone analogs.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development, validation, and quality control of steroid products.
• Biochemical Research: Serves as a precursor or standard in studies involving steroid biosynthesis, metabolism, and receptor interaction.
• Sapogenin Derivative Synthesis: A key starting material for the preparation of various sapogenins and their modified analogs for industrial and research purposes.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals in the fine chemical sector.

Basic Information

Product Name	(20β,25R)-5α-Spirostan-3-One
CAS No.	55028-78-9
Molecular Formula	C27H42O3
Molecular Weight	414.62 g/mol
Synonyms	(20β,25R)-Spirostan-3-one; 5α-Spirostan-3-one, (20β,25R)-; (25R)-5α-Spirostan-3β-ol-11-one (related); Tigogenone (isomer); Neotigogenone (related compound); 3-Oxospirostan; Spirostan-3-one derivative
EINECS	Contact for details

Quality Control

Every batch of (20β,25R)-5α-Spirostan-3-One is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure identity, purity, and consistency meet the high standards required for pharmaceutical intermediates and research chemicals. A detailed Certificate of Analysis (COA) providing specifications for identity (IR, NMR), assay (HPLC), and related substances is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.