Description

Physalin D is a naturally occurring, bioactive withanolide compound isolated from plants of the *Physalis* genus. This high-purity reference standard is critical for pharmaceutical research and development, particularly in the study of anti-inflammatory, anti-tumor, and immunomodulatory activities. It serves as an essential analytical standard for researchers and quality control laboratories in the pharmaceutical, nutraceutical, and academic sectors requiring precise compound identification and quantification.

Application

• Pharmaceutical Reference Standard: Primary use as a certified reference material (CRM) for the identification, assay, and impurity profiling of herbal extracts and finished products in quality control laboratories.
• Bioactivity Research: Key compound for in-vitro and in-vivo studies investigating anti-cancer, anti-inflammatory, and immunomodulatory mechanisms of action.
• Natural Product Isolation & Analysis: Serves as a benchmark in the isolation, purification, and structural elucidation of withanolides from plant sources using techniques like HPLC, LC-MS, and NMR.
• Herbal Medicine Standardization: Used to standardize and authenticate herbal formulations containing *Physalis* species, ensuring batch-to-batch consistency and efficacy.
• Academic & Contract Research: Essential reagent for universities and CROs (Contract Research Organizations) conducting pharmacological and phytochemical research.

Basic Information

Product Name	Physalin D
CAS No.	54980-22-2
Molecular Formula	C₂₈H₃₀O₁₀
Molecular Weight	526.53 g/mol
Synonyms	5,6-Epoxy-4β,14α,20β,24ξ,25-pentahydroxy-1-oxoergosta-2,22-dien-26-oic acid γ-lactone; Physalin D (from *Physalis alkekengi*); Withanolide D (related class); 14,20-Epoxy-4,5,6,14,20,24-hexahydroxy-1-oxo-3,22-withadien-26-oic acid γ-lactone
EINECS	Contact for details

Quality Control

Every batch of Physalin D is manufactured and analyzed under strict quality management systems. Our products undergo rigorous identity confirmation, purity analysis, and impurity profiling using advanced chromatographic and spectroscopic methods to ensure they meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identification tests, and chromatographic data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at -20°C under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.