Description

Adamantane-1-Carbonyl Isothiocyanate is a high-purity, functionalized adamantane derivative that serves as a critical building block in advanced organic synthesis. Its unique rigid cage structure combined with a reactive isothiocyanate group makes it invaluable for creating novel materials and bioactive compounds with enhanced stability. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing new drug candidates, ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antiviral and central nervous system (CNS) active pharmaceutical ingredients (APIs) leveraging the adamantane scaffold.
• Agrochemical Research: Used to develop new classes of pesticides and herbicides with improved metabolic stability and efficacy.
• Material Science: Building block for creating advanced polymers, dendrimers, and metal-organic frameworks (MOFs) with tailored thermal and mechanical properties.
• Chemical Biology & Proteomics: Acts as a versatile coupling agent for bioconjugation and affinity labeling of proteins and other biomolecules.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and molecular recognition applications.
• High-Performance Liquid Chromatography (HPLC) Chiral Stationary Phases: Serves as a derivatization agent or a component in chiral selectors.

Basic Information

Product Name	Adamantane-1-Carbonyl Isothiocyanate
CAS No.	54979-99-6
Molecular Formula	C12H15NOS
Molecular Weight	221.32 g/mol
Synonyms	1-Adamantanecarbonyl isothiocyanate; 1-Isothiocyanatocarbonyladamantane; Adamantane-1-carboxylic acid isothiocyanate; Tricyclo[3.3.1.13,7]decane-1-carbonyl isothiocyanate; 1-Adamantylcarbonyl isothiocyanate; NSC 334363; Adamantoyl isothiocyanate
EINECS	Contact for details

Quality Control

Every batch of Adamantane-1-Carbonyl Isothiocyanate is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for research and fine chemical intermediates. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles as determined by techniques like HPLC, NMR, and IR, is provided with each shipment to guarantee reliable and consistent performance in your applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.