Description

2',3'-Dialdehyde Atp is a chemically modified derivative of adenosine triphosphate (ATP), featuring reactive aldehyde groups at the 2' and 3' positions of the ribose sugar. This functionalization makes it a valuable cross-linking reagent and a key intermediate in the synthesis of nucleotide-protein conjugates and affinity probes. It is primarily utilized by researchers and manufacturers in biochemistry, molecular biology, and pharmaceutical development for studying enzyme mechanisms and developing targeted diagnostic tools.

Application

• Biochemical Research: As a critical intermediate for synthesizing affinity labels and probes to study ATP-binding sites on enzymes and receptors.
• Pharmaceutical Development: Used in the creation of nucleotide-based drug conjugates and targeted therapeutic agents.
• Diagnostic Reagent Synthesis: Serves as a precursor for manufacturing labeled nucleotides used in diagnostic assays and imaging.
• Enzyme Mechanism Studies: Employed as an irreversible inhibitor or cross-linker to elucidate the structure and function of kinases and other ATP-utilizing enzymes.
• Bioconjugation: The reactive aldehyde groups enable site-specific conjugation to proteins, peptides, or solid supports for various biotechnological applications.
• Material Science: Potential use in developing functionalized surfaces or nanomaterials for biosensing platforms.

Basic Information

Product Name	2',3'-Dialdehyde Atp
CAS No.	54970-91-1
Molecular Formula	C10H12N5O12P3
Molecular Weight	511.13 g/mol
Synonyms	2',3'-O-Dialdehyde Adenosine 5'-Triphosphate; Periodate-Oxidized ATP; oATP; ATP Dialdehyde; Adenosine 5'-triphosphate 2',3'-dialdehyde; 2',3'-Dicarboxyaldehyde ATP; Oxidized ATP; ATP-2',3'-dial
EINECS	Contact for details

Quality Control

Our 2',3'-Dialdehyde Atp is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. For specific purity requirements or custom synthesis, please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to equilibrate to room temperature before opening to prevent condensation. For long-term stability, store under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (Karl Fischer)	≤ 3.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.