Description

4-Azidobutan-1-ol is a versatile bifunctional organic compound featuring both an azido group and a primary hydroxyl group, making it a valuable click chemistry reagent and a key building block for chemical synthesis. Its unique structure enables efficient, high-yield conjugation reactions under mild conditions, which is critical for developing advanced materials and bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, bioconjugation, and polymer science industries seeking to create novel drug candidates, functionalized surfaces, or tailored macromolecular architectures.

Application

• Click Chemistry Reagent: Used in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for the rapid and reliable synthesis of 1,2,3-triazoles.
• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, including linkers for antibody-drug conjugates (ADCs) and prodrugs.
• Bioconjugation: Enables the site-specific labeling and modification of proteins, peptides, nucleic acids, and other biomolecules for diagnostic and therapeutic applications.
• Polymer & Material Science: Acts as a functional monomer or cross-linking agent for creating advanced polymers, hydrogels, and surface-modified materials with tailored properties.
• Chemical Probe Synthesis: Utilized to develop activity-based probes for studying enzyme function and biological pathways in chemical biology.
• Agrochemical Research: Employed as an intermediate in the development of novel crop protection agents and plant growth regulators.

Basic Information

Product Name	4-Azidobutan-1-ol
CAS No.	54953-78-5
Molecular Formula	C4H9N3O
Molecular Weight	115.13 g/mol
Synonyms	4-Azido-1-butanol; 1-Azido-4-hydroxybutane; 4-Hydroxybutyl azide; ω-Azidobutanol; Butane-1,4-diol monoazide; N3(CH2)4OH; 4-Azidobutanol
EINECS	Contact for details

Quality Control

Our 4-Azidobutan-1-ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to verify identity, potency, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with our stringent internal specifications. We support cGMP production for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and potentially shock-sensitive azide functional group, handle with appropriate precautions and avoid exposure to heat, strong acids, and heavy metals. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.