Description

1-Deoxy-1-(3,4-Dihydro-2,4-Dioxo-1(2H)-Pyrimidinyl)-β-D-Ribofuranur Onamide is a high-purity nucleoside analog derivative, a critical building block in advanced pharmaceutical synthesis and biochemical research. Its primary value lies in its role as a key intermediate for the development of novel antiviral and anticancer therapeutics, where precise molecular structure is paramount. This compound is essential for R&D laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in nucleoside-based drug discovery and process development.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of modified nucleoside analogs for antiviral and anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and DNA/RNA synthesis pathways.
• Process Chemistry: Serves as a starting material or advanced intermediate in the scale-up and optimization of active pharmaceutical ingredient (API) manufacturing processes.
• Proteomics & Genomics: Potential utility in the development of probes or tools for studying nucleic acid interactions and cellular processes.
• Academic Research: Employed in university and institutional labs for investigating the structure-activity relationships of nucleoside derivatives.
• Custom Synthesis: Basis for the custom manufacturing of specialized nucleoside compounds for client-specific research and development projects.

Basic Information

Product Name	1-Deoxy-1-(3,4-Dihydro-2,4-Dioxo-1(2H)-Pyrimidinyl)-β-D-Ribofuranur Onamide
CAS No.	54918-02-4
Molecular Formula	C12H15N3O7
Molecular Weight	313.27 g/mol
Synonyms	1-(2,4-Dioxo-3,4-dihydro-1(2H)-pyrimidinyl)-1-deoxy-β-D-ribofuranuronamide; 1-Deoxy-1-(2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl)-β-D-ribofuranuronic acid amide; β-1'-Deoxy-1'-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)ribofuranuronamide; 1-(β-D-Ribofuranosyl)dihydro-2,4(1H,3H)-pyrimidinedione-1-carboxamide; Dihydrouridine derivative; Nucleoside analog intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1-Deoxy-1-(3,4-Dihydro-2,4-Dioxo-1(2H)-Pyrimidinyl)-β-D-Ribofuranur Onamide is manufactured under strict quality management systems. Products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing all critical specifications. Our quality commitment supports applications requiring high standards, including cGMP-grade material for pharmaceutical development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.