Description

Chlorozotocin CAS NO 54749-90-5 is a nitrosourea-based alkylating agent and a derivative of streptozotocin. This compound is of significant interest in biochemical and pharmaceutical research due to its potent DNA cross-linking properties. It is primarily utilized by researchers in oncology and medicinal chemistry for investigating novel chemotherapeutic agents and studying mechanisms of cytotoxicity.

Application

• Oncology Research: Used as a reference standard and experimental compound in the study of DNA alkylation and anti-tumor mechanisms.
• Biochemical Studies: Employed in laboratory settings to investigate cellular apoptosis and DNA damage response pathways.
• Pharmaceutical Development: Serves as a key intermediate or model compound in the research and development of new nitrosourea-based chemotherapeutics.
• Academic Research: Utilized in universities and research institutes for fundamental studies in chemical biology and cancer pharmacology.

Basic Information

Product Name	Chlorozotocin
CAS No.	54749-90-5
Molecular Formula	C9H16ClN3O7
Molecular Weight	313.70 g/mol
Synonyms	1-(2-Chloroethyl)-3-((2-deoxy-α-D-glucopyranosyl)methyl)-1-nitrosourea; NSC 178248; DCNU; Chlorozotocin; 1-(2-Chloroethyl)-3-(2-deoxy-α-D-glucopyranos-2-yl)-1-nitrosourea; 1-(2-Chloroethyl)-3-(2-deoxy-α-D-glucopyranosyl)methyl-1-nitrosourea
EINECS	Contact for details

Quality Control

Our Chlorozotocin is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.