Description

Echinocandin B is a potent, naturally occurring lipopeptide antifungal agent belonging to the echinocandin class. This compound serves as the crucial chemical precursor for the semi-synthetic production of several clinically important antifungal drugs, including Anidulafungin. Its value lies in its unique mechanism of action, which targets fungal cell wall synthesis, offering a vital therapeutic pathway. This product is essential for pharmaceutical R&D laboratories, API manufacturers, and biotechnology companies engaged in the development and production of advanced antifungal therapeutics.

Application

• Pharmaceutical Intermediate: Primary use as the key starting material for the synthesis of advanced antifungal APIs like Anidulafungin.
• Antifungal Research: A critical reference standard and tool compound for in-vitro and in-vivo studies on fungal pathogens, including Candida and Aspergillus species.
• Biochemical Studies: Used to investigate the mechanism of action of glucan synthase inhibition and fungal cell wall biosynthesis.
• Process Development: Employed in the optimization and scale-up of fermentation and purification processes for echinocandin-type compounds.
• Quality Control: Serves as a high-purity analytical standard for the identification and assay of related pharmaceutical products.

Basic Information

Product Name	Echinocandin B
CAS No.	54651-05-7
Molecular Formula	C52H81N7O15
Molecular Weight	1052.2 g/mol
Synonyms	Echinocandin B; Antibiotic A 30912; A30912; Pneumocandin B0; (4R,5R)-4,5-Dihydroxy-N2-[(1S,2S)-1-hydroxy-2-hydroxy-1-(4-hydroxy-1-oxopentyl)-2-(1H-indol-3-yl)ethyl]-L-ornithyl-1-(4-hydroxypentyl)-L-threonyl-3-[(3S)-3-hydroxy-L-ornithyl]-4-methyl-L-proline Cyclic (6→1)-Peptide; LY-121019; Anidulafungin Impurity A; Anidulafungin Intermediate
EINECS	Contact for details

Quality Control

Our Echinocandin B is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical development. Each lot undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and stringent control of related substances. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or under refrigeration (2-8°C) as specified. Due to its hygroscopic nature, the container must be kept in a dry environment. For long-term storage, consider desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0% Any single unknown impurity ≤ 1.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Specific Rotation	Contact for details
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.