Description

8-Tempo-Aminoadenosine Cyclic 3’5’Monophosphate is a chemically modified derivative of cyclic adenosine monophosphate (cAMP), a fundamental secondary messenger in cellular signaling. This compound is valued for its enhanced stability and utility as a biochemical tool in research applications. It is primarily sought by researchers and manufacturers in the pharmaceutical, biotechnology, and life science research sectors for investigating cell signaling pathways and developing novel therapeutic agents.

Application

• Biochemical Research: Used as a stable analog of cAMP to study protein kinase A (PKA) activation and other cAMP-mediated signaling cascades in vitro and in cell culture.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the research and development of drugs targeting cardiovascular, metabolic, and neurological disorders.
• Cell Biology Studies: Employed to modulate intracellular cAMP levels to examine effects on cell proliferation, differentiation, and gene expression.
• Diagnostic Reagent Manufacturing: Utilized in the formulation of enzyme-linked immunosorbent assay (ELISA) kits and other diagnostic assays for research purposes.
• Signal Transduction Analysis: Acts as a critical tool for elucidating the role of cAMP in hormone action, neurotransmission, and immune response mechanisms.

Basic Information

Product Name	8-Tempo-Aminoadenosine Cyclic 3’5’Monophosphate
CAS No.	54606-91-6
Molecular Formula	C15H22N7O7P
Molecular Weight	467.36 g/mol
Synonyms	8-[(2,2,6,6-Tetramethylpiperidin-1-yl)oxy]adenosine-3',5'-cyclic monophosphate; 8-TEMPO-cAMP; 8-AminoTEMPO-cAMP; cAMP-TEMPO conjugate; Cyclic AMP TEMPO derivative; 8-(1-Oxyl-2,2,6,6-tetramethylpiperidin-4-yl)aminoadenosine cyclic 3',5'-phosphate; Adenosine, 8-[[(2,2,6,6-tetramethyl-1-oxyl-4-piperidinyl)amino]]-, cyclic 3',5'-(hydrogen phosphate)
EINECS	Contact for details

Quality Control

Our 8-Tempo-Aminoadenosine Cyclic 3’5’Monophosphate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-purity research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, Methanol; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.