Description

5-[(6,7,8-Trimethoxyquinazolin-4-Yl)Amino]Pentyl Nitrate, Maleate is a high-purity, synthetic organic compound belonging to the quinazoline class, specifically formulated as a maleate salt. This compound is of significant interest for its potential as a key pharmaceutical intermediate in the research and development of novel therapeutic agents. It is primarily utilized by R&D laboratories and pharmaceutical manufacturers engaged in the synthesis of specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel quinazoline-based drug candidates.
• Vasodilator Research: Used in preclinical research for developing compounds targeting cardiovascular diseases, leveraging its nitrate ester moiety.
• Kinase Inhibitor Development: Acts as a precursor in the creation of potential tyrosine kinase or phosphodiesterase inhibitors for oncology and other therapeutic areas.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Academic & Institutional Research: Utilized in universities and research institutes for studying structure-activity relationships (SAR) in medicinal chemistry.
• Process Chemistry: Used in scale-up and optimization studies for the commercial production of advanced pharmaceutical intermediates.

Basic Information

Product Name	5-[(6,7,8-Trimethoxyquinazolin-4-Yl)Amino]Pentyl Nitrate, Maleate
CAS No.	54567-65-6
Molecular Formula	C₂₀H₂₈N₅O₉ • C₄H₄O₄
Molecular Weight	Contact for details
Synonyms	5-[(6,7,8-Trimethoxy-4-quinazolinyl)amino]pentyl nitrate maleate
Pentyl nitrate, 5-[(6,7,8-trimethoxy-4-quinazolinyl)amino]-, (Z)-2-butenedioate (1:1)
5-((6,7,8-Trimethoxyquinazolin-4-yl)amino)pentyl nitrate maleate salt
L-NAME related quinazoline nitrate ester
Quinazoline nitrate derivative
CAS 54567-65-6
EINECS	Contact for details

Quality Control

Our 5-[(6,7,8-Trimethoxyquinazolin-4-Yl)Amino]Pentyl Nitrate, Maleate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and development use. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants and storing under an inert atmosphere to prevent oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.