Description

[[2-[(E)-1-Methyl-1-Propenyl]-1,3-Dioxolan-2-Yl]Methyl]Phosphonic Acid Diethyl Ester is a specialized organophosphorus compound featuring a unique dioxolane-protected functional group. This chemical matters as a versatile building block and intermediate in advanced organic synthesis, offering a reactive phosphonate ester moiety for carbon-phosphorus bond formation. Industrial researchers and process chemists need it for developing novel agrochemicals, pharmaceuticals, and functional materials where precise molecular architecture is critical.

Application

• Agrochemical Intermediate: Key precursor in the synthesis of novel herbicides, insecticides, and plant growth regulators utilizing its phosphonate functionality.
• Pharmaceutical Synthesis: Serves as a crucial building block for creating potential drug candidates, especially in nucleotide and prodrug chemistry.
• Ligand and Catalyst Development: Used in the preparation of specialized phosphonate-based ligands for metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of flame retardants, polymer modifiers, and other functional materials requiring phosphorus incorporation.
• Organic Synthesis Reagent: Acts as a reagent in Horner-Wadsworth-Emmons (HWE) olefination reactions and other carbon-carbon bond-forming transformations.
• Chemical Biology Probes: Potential use in synthesizing activity-based probes and molecular tools for studying biological phosphate-related processes.

Basic Information

Product Name	[[2-[(E)-1-Methyl-1-Propenyl]-1,3-Dioxolan-2-Yl]Methyl]Phosphonic Acid Diethyl Ester
CAS No.	54543-05-4
Molecular Formula	C₁₄H₂₇O₅P
Molecular Weight	306.34 g/mol
Synonyms	Diethyl [[2-[(1E)-1-Methyl-1-propen-1-yl]-1,3-dioxolan-2-yl]methyl]phosphonate; Diethyl (2-[(E)-1-Methylprop-1-en-1-yl]-1,3-dioxolan-2-ylmethyl)phosphonate; Phosphonic acid, [[2-[(1E)-1-methyl-1-propen-1-yl]-1,3-dioxolan-2-yl]methyl]-, diethyl ester; (2-[(E)-1-Methylprop-1-enyl]-1,3-dioxolan-2-ylmethyl)phosphonic acid diethyl ester; Acetaldehyde, (2-diethoxyphosphinylmethyl-1,3-dioxolan-2-yl)-, dimethyl acetal (related form); A potential Horner-Wadsworth-Emmons reagent.
EINECS	Contact for details

Quality Control

Our [[2-[(E)-1-Methyl-1-Propenyl]-1,3-Dioxolan-2-Yl]Methyl]Phosphonic Acid Diethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all critical parameters are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.