Description

Thiopurinol Ribonucleoside is a synthetic nucleoside analog of significant interest in biochemical and pharmaceutical research. This compound serves as a key intermediate and reference standard in the development of novel therapeutic agents, particularly those targeting metabolic pathways and nucleic acid synthesis. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in antiviral and anticancer drug discovery programs.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of novel purine-based therapeutics.
• Biochemical Research: Used as a reference standard and tool compound for studying enzyme kinetics and inhibition, particularly involving purine metabolism.
• Antiviral Drug Development: Investigated as a precursor for nucleoside analogs with potential activity against viral replication.
• Oncology Research: Serves as a starting material for the development of chemotherapeutic agents targeting DNA/RNA synthesis in cancer cells.
• Metabolic Pathway Studies: Employed in research to elucidate and modulate specific enzymatic pathways within cells.
• Fine Chemical Synthesis: A valuable synthon for the custom synthesis of more complex, specialized nucleoside derivatives.

Basic Information

Item	Detail
Product Name	Thiopurinol Ribonucleoside
CAS No.	54524-71-9
Molecular Formula	C10H12N4O5S
Molecular Weight	300.29 g/mol
Synonyms	6-Thiopurinol ribonucleoside; 6-Mercaptopurine ribonucleoside; 6-Thioinosine; 6-MP riboside; Thioinosine; NSC 49164; 9-β-D-Ribofuranosyl-6-mercaptopurine; 6-Thio-9-β-D-ribofuranosylpurine
EINECS	Contact for details

Quality Control

Our Thiopurinol Ribonucleoside is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR). We provide full traceability and a Certificate of Analysis (COA) with every shipment, detailing all critical quality attributes to ensure it meets the exacting standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.