Description

(20ξ)-5α-Cholest-22-Ene CAS NO 54514-99-7 is a high-purity steroidal intermediate characterized by its specific cholestane backbone with a double bond at the 22-position. This compound is of significant value in pharmaceutical research and fine chemical synthesis, serving as a crucial building block for the development of more complex steroid derivatives and active pharmaceutical ingredients (APIs). It is primarily required by research institutions, pharmaceutical development laboratories, and manufacturers specializing in steroid-based therapeutics and advanced organic synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel steroid-based drugs and hormone analogs.
• Biochemical Research: Used as a reference standard or starting material in metabolic pathway studies and receptor binding assays.
• Fine Chemical Synthesis: Serves as a chiral building block for constructing complex natural products and specialty chemicals.
• Academic Research: Employed in university and institutional labs for organic chemistry methodology development and structural studies.
• API Development: Integral in the research and development pipeline for new Active Pharmaceutical Ingredients targeting endocrine and metabolic disorders.

Basic Information

Product Name	(20ξ)-5α-Cholest-22-Ene
CAS No.	54514-99-7
Molecular Formula	C₂₇H₄₆
Molecular Weight	370.66 g/mol
Synonyms	5α-Cholest-22-ene; (20ξ)-5α-Cholest-22-ene; 22-Dehydro-5α-cholestane; Cholest-22-ene, 5α-; 5α-Cholest-22-ene (20ξ)-; 5α-Cholest-22-ene (20ξ)-; (20ξ)-Cholest-22-ene; 5α,22-Cholestadiene (related structure)
EINECS	Contact for details

Quality Control

Our (20ξ)-5α-Cholest-22-Ene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC, GC, and NMR to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes. Our quality systems are designed to support cGMP-compliant applications where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent contamination and minimize exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Specification available upon request
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.