Description

(22E)-5α-Cholest-22-Ene CAS NO 54514-98-6 is a high-purity steroidal alkene of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a crucial chiral building block and intermediate for the development of novel steroid-based therapeutics and bioactive molecules. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in steroid chemistry, drug discovery, and the synthesis of complex natural products.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel steroid-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a standard or probe in studies investigating sterol metabolism, membrane biophysics, and receptor-ligand interactions.
• Organic Synthesis: Serves as a versatile building block for constructing complex steroidal frameworks with specific stereochemistry.
• Reference Standard: Employed as a high-purity analytical standard in chromatographic methods (HPLC, GC) for quality control and method development.
• Material Science Research: Investigated for potential applications in the development of advanced liquid crystals and functional organic materials.

Basic Information

Product Name	(22E)-5α-Cholest-22-Ene
CAS No.	54514-98-6
Molecular Formula	C₂₇H₄₆
Molecular Weight	370.66 g/mol
Synonyms	(22E)-Cholest-22-ene; 5α-Cholest-22-ene; (22E)-5α-Cholest-22-ene; 22-Dehydrocholesterol (unspecified isomer); Cholesta-5,22-diene (related); Steroidal alkene C27; 5α-Cholest-22(23)-ene
EINECS	Contact for details

Quality Control

Our (22E)-5α-Cholest-22-Ene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable performance in your sensitive applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Specification available upon request
Specific Rotation	Specification available upon request
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.