Description

2,2-(Ethylenebisthio)-5α-Androstan-11-One CAS NO 54498-87-2 is a specialized steroidal thioketal derivative, serving as a critical advanced intermediate in pharmaceutical synthesis. Its unique chemical structure, featuring the ethylenebisthio moiety, makes it a valuable building block for the development of novel therapeutic agents, particularly in the field of endocrinology and hormone-related research. This high-purity compound is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on creating next-generation steroid-based pharmaceuticals.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex steroidal drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new steroid analogs with modified biological activity.
• Hormone Analog Synthesis: Employed in the creation of novel androgen or other hormone receptor modulators due to its modified steroidal backbone.
• Fine Chemical Production: Serves as a building block in custom synthesis and contract manufacturing for specialized chemical entities.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	2,2-(Ethylenebisthio)-5α-Androstan-11-One
CAS No.	54498-87-2
Molecular Formula	C21H32OS2
Molecular Weight	364.61 g/mol
Synonyms	11-Oxo-5α-androstane-2,2-diyl ethylenebis(thioate); 5α-Androstan-11-one, 2,2-(ethylenedithio)-; 2,2'-(Ethylenedithio)bis(5α-androstan-11-one); Androstane thioketal derivative; Steroidal ethylenebisthio ketal; ETBO; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our 2,2-(Ethylenebisthio)-5α-Androstan-11-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability, consistency, and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.