Description

4-Azidobutyric Acid is a versatile bifunctional organic compound featuring both a carboxylic acid and an azide functional group. This unique structure makes it a valuable click chemistry reagent and a critical building block for the synthesis of more complex molecules. It is primarily used by researchers and manufacturers in the pharmaceutical, bioconjugation, and materials science sectors to develop novel drug candidates, labeled biomolecules, and functional polymers.

Application

• Click Chemistry Reagent: Used in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and polymer functionalization.
• Pharmaceutical Intermediate: Serves as a key synthon in the development of prodrugs and active pharmaceutical ingredients (APIs) with targeted delivery mechanisms.
• Bioconjugation Linker: Facilitates the covalent attachment of dyes, probes, or drugs to proteins, antibodies, and other biomolecules for diagnostic and therapeutic applications.
• Polymer Modification: Employed to introduce azide functionalities into polymer backbones or side chains, enabling the creation of smart materials and hydrogels.
• Peptide Synthesis: Used as a protected or activated derivative for the solid-phase or solution-phase synthesis of modified peptides.
• Chemical Biology Probes: Integral for synthesizing activity-based probes to study enzyme function and metabolic pathways.

Basic Information

Product Name	4-Azidobutyric Acid
CAS No.	54447-68-6
Molecular Formula	C4H7N3O2
Molecular Weight	129.12 g/mol
Synonyms	4-Azidobutanoic Acid; γ-Azidobutyric Acid; Butanoic acid, 4-azido-; 4-Azido-butyric acid; Azidobutanoic acid; N3(CH2)3COOH
EINECS	Contact for details

Quality Control

Our 4-Azidobutyric Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to the presence of the azide functional group, appropriate safety measures for handling azide compounds should be observed.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.