Description

20,21-Epoxy-20-Methyl-5α-Pregnane is a high-purity steroid derivative and a key synthetic intermediate in advanced organic chemistry. This compound is valued for its defined stereochemistry and functionalized pregnane backbone, which serves as a crucial building block for the synthesis of complex bioactive molecules. It is primarily sought by research institutions and pharmaceutical development companies engaged in the creation of novel therapeutic agents and reference standards.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of specialized steroid-based active pharmaceutical ingredients (APIs) and drug candidates.
• Biochemical Research: Used as a reference standard or a starting material in metabolic pathway studies and steroid hormone research.
• Organic Synthesis: Serves as a versatile chiral building block for constructing complex molecular architectures in medicinal chemistry programs.
• Analytical Standard: Employed as a high-purity calibrant or internal standard in chromatographic (HPLC, GC) and spectroscopic analysis methods.

Basic Information

Product Name	20,21-Epoxy-20-Methyl-5α-Pregnane
CAS No.	54411-89-1
Molecular Formula	C23H36O2
Molecular Weight	344.53 g/mol
Synonyms	20,21-Epoxy-20-methylpregnane; 20-Methyl-20,21-epoxy-5α-pregnane; 20,21α-Epoxy-20β-methyl-5α-pregnane; 20β-Methyl-20,21α-epoxy-5α-pregnane; 5α-Pregnane, 20,21-epoxy-20-methyl-; Pregnane, 20,21-epoxy-20-methyl-; 20,21-Epoxy-20-methyl-5α-pregnane (8CI)
EINECS	Contact for details

Quality Control

Our 20,21-Epoxy-20-Methyl-5α-Pregnane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and synthesis applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.