Description

3α-Hydroxy-5β-Cholan-12-One is a high-purity steroidal intermediate of significant importance in organic synthesis. This compound matters as a versatile building block for the development of more complex bioactive molecules, particularly in pharmaceutical research. It is primarily needed by manufacturers and R&D laboratories in the pharmaceutical, fine chemical, and life science sectors for the synthesis of steroid derivatives and other specialized compounds.

Application

• Pharmaceutical Intermediate: A key starting material or intermediate in the synthesis of steroid-based active pharmaceutical ingredients (APIs) and drug candidates.
• Fine Chemical Synthesis: Used as a chiral building block for constructing complex organic molecules in research and development.
• Biochemical Research: Employed in metabolic studies and as a reference standard for analytical purposes in laboratory settings.
• Steroid Derivative Production: Serves as a precursor for manufacturing modified bile acids and other steroidal compounds with specific biological activities.

Basic Information

Product Name	3α-Hydroxy-5β-Cholan-12-One
CAS No.	54411-58-4
Molecular Formula	C₂₄H₃₈O₃
Molecular Weight	374.56 g/mol
Synonyms	12-Oxolithocholic Acid; 3α-Hydroxy-12-oxo-5β-cholan-24-oic Acid; 12-Ketolithocholic Acid; 3α-Hydroxy-12-oxo-5β-cholanic Acid; 12-Oxo-3α-hydroxy-5β-cholan-24-oic Acid; 3α-Hydroxy-12-oxolithocholic Acid; 12-Keto-3α-hydroxy-5β-cholanic Acid
EINECS	Contact for details

Quality Control

Our 3α-Hydroxy-5β-Cholan-12-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.