Description

1H-Indole-1-Carbonyl Chloride, Octahydro-2-Methyl- (9Ci) is a specialized heterocyclic building block and reactive intermediate of significant interest in advanced organic synthesis. Its value lies in its role as a key acylating agent for introducing the octahydro-2-methylindole scaffold, a privileged structure in medicinal chemistry. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of complex molecules targeting central nervous system (CNS) disorders, cardiovascular diseases, and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging the biological activity of the indoline core.
• Chemical Research & Development: Serves as a versatile scaffold for constructing diverse compound libraries in drug discovery and material science programs.
• Peptidomimetic Chemistry: Employed to create conformationally constrained peptide analogs by incorporating the saturated indole moiety.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands used in asymmetric catalysis.
• Fine Chemical Production: Utilized in the multi-step synthesis of high-value, low-volume specialty chemicals.

Basic Information

Product Name	1H-Indole-1-Carbonyl Chloride, Octahydro-2-Methyl- (9Ci)
CAS No.	54395-71-0
Molecular Formula	C10H14ClNO
Molecular Weight	199.68 g/mol
Synonyms	Octahydro-2-methyl-1H-indole-1-carbonyl chloride; 2-Methyloctahydroindole-1-carbonyl chloride; 1-Carboxylyl chloride-2-methyloctahydroindole; (2-Methyloctahydroindol-1-yl)carbonyl chloride; 1H-Indole-1-carbonyl chloride, octahydro-2-methyl-
EINECS	Contact for details

Quality Control

Our production of 1H-Indole-1-Carbonyl Chloride, Octahydro-2-Methyl- (9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic processes. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and acid chloride nature, it must be kept under an inert atmosphere (e.g., nitrogen or argon) and protected from moisture to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.