Description

Cyclopropylacetyl Chloride is a versatile and highly reactive acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the cyclopropyl moiety, which is prized for its ability to modulate the physicochemical and metabolic properties of target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, enabling the synthesis of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, cardiovascular diseases, and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the cyclopropyl group enhances biological activity and environmental stability.
• Material Science Precursor: Employed in the synthesis of specialized polymers, liquid crystals, and organic electronic materials requiring unique steric and electronic properties.
• Peptide Mimetics & Bioconjugation: Facilitates the introduction of the cyclopropane ring into peptide backbones or serves as a linker for bioconjugation strategies in drug discovery.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D for exploring new chemical spaces and developing novel synthetic methodologies.
• Flavor & Fragrance Industry: Intermediate for synthesizing complex aroma chemicals with unique olfactory profiles.

Basic Information

Product Name	Cyclopropylacetyl Chloride
CAS No.	54322-65-5
Molecular Formula	C5H7ClO
Molecular Weight	118.56 g/mol
Synonyms	Cyclopropanecarbonyl Chloride; Cyclopropanecarboxylic Acid Chloride; Cyclopropanoyl Chloride; Cyclopropyl Carbonyl Chloride; Cyclopropane-1-carbonyl chloride; Cyclopropanecarboxychloride; Cyclopropanecarboxylic chloride; 1-Cyclopropanecarbonyl chloride
EINECS	Contact for details

Quality Control

Our Cyclopropylacetyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (IR, NMR), to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment. We adhere to cGMP principles where applicable to support our customers in regulated markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated) for long-term stability. This product is hygroscopic (moisture-sensitive) and reacts vigorously with water, alcohols, and bases. Keep the container tightly sealed under an inert atmosphere (nitrogen/argon) to prevent degradation from moisture and ensure maximum shelf life.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density	~1.15 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.