Description

1,3-Dithiane-2-Carbonyl Chloride (9Ci) is a versatile and highly reactive organosulfur building block, primarily used as a key acyl anion equivalent in organic synthesis. Its core value lies in enabling the formation of complex molecular architectures, particularly in the synthesis of pharmaceuticals and advanced materials, through its unique masked carbonyl functionality. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of complex drug molecules, particularly those containing thioacetal or modified carbonyl groups.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its reactivity to create unique bioactive structures.
• Material Science: Serves as a precursor for functional polymers and advanced materials where sulfur-containing moieties are required for specific properties.
• Organic Synthesis Reagent: Acts as a versatile reagent for Umpolung chemistry, enabling the nucleophilic acylation of electrophiles in multi-step synthetic sequences.
• Peptide Mimetics & Bioconjugation: Utilized in the development of peptide analogs and for creating bioconjugates due to its reactive acid chloride group.
• Catalyst & Ligand Development: Employed in the synthesis of novel chiral ligands and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	1,3-Dithiane-2-Carbonyl Chloride (9Ci)
CAS No.	54235-69-7
Molecular Formula	C5H7ClOS2
Molecular Weight	182.69 g/mol
Synonyms	2-(Chlorocarbonyl)-1,3-dithiane; 1,3-Dithiane-2-carbonyl chloride; 2-Carboxy-1,3-dithiane chloride; 1,3-Dithian-2-ylcarbonyl chloride; 2-Dithianecarbonyl chloride; NSC 334058; 2-(Chloroformyl)-1,3-dithiane
EINECS	Contact for details

Quality Control

Our 1,3-Dithiane-2-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.