Description

2-(4-Chlorophenyl)-4-Methyl-1,3-Thiazole-5-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its value lies in its role as a key building block for constructing complex heterocyclic molecules with specific biological activities. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole core.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Employed in the creation of molecular probes and labeled compounds for biochemical and pharmacological studies.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical companies offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	2-(4-Chlorophenyl)-4-Methyl-1,3-Thiazole-5-Carbonyl Chloride
CAS No.	54001-22-8
Molecular Formula	C11H7Cl2NOS
Molecular Weight	272.15 g/mol
Synonyms	5-Carbonyl Chloride-2-(4-chlorophenyl)-4-methyl-1,3-thiazole; 2-(p-Chlorophenyl)-4-methyl-1,3-thiazole-5-carbonyl chloride; 4-Methyl-2-(4-chlorophenyl)-1,3-thiazole-5-carbonyl chloride; 1,3-Thiazole-5-carbonyl chloride, 2-(4-chlorophenyl)-4-methyl-; 54001-22-8; 2-(4-Chlorophenyl)-4-methylthiazole-5-carbonyl chloride; p-Chlorophenyl-4-methylthiazole-5-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 2-(4-Chlorophenyl)-4-Methyl-1,3-Thiazole-5-Carbonyl Chloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released using advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.