Description

4-Methyl-2-Phenyl-1,3-Thiazole-5-Carbonyl Chloride is a high-purity, reactive organic intermediate essential for advanced chemical synthesis. Its value lies in its role as a key building block for constructing complex heterocyclic molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those containing the thiazole pharmacophore for therapeutic applications.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides where the thiazole ring contributes to biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialized polymers and organic electronic materials.
• Ligand and Catalyst Development: Employed to synthesize complex ligands for metal catalysis and organocatalysts used in asymmetric synthesis.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing heterocyclic dyes with specific light-absorption properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule construction.

Basic Information

Product Name	4-Methyl-2-Phenyl-1,3-Thiazole-5-Carbonyl Chloride
CAS No.	54001-18-2
Molecular Formula	C11H8ClNOS
Molecular Weight	237.70 g/mol
Synonyms	5-Carbonyl Chloride-4-Methyl-2-Phenylthiazole; 2-Phenyl-4-methyl-1,3-thiazole-5-carbonyl chloride; 4-Methyl-2-phenyl-5-thiazolecarbonyl chloride; 5-Thiazolecarbonyl chloride, 4-methyl-2-phenyl-; Thiazole-5-carbonyl chloride, 4-methyl-2-phenyl-; 54001-18-2; 4-Methyl-2-phenylthiazole-5-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-Phenyl-1,3-Thiazole-5-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.