Description

1,2-Cyclopropanedicarbonyl Dichloride, 3-Methyl-, (1Alpha,2Beta,3Alpha)- (9Ci) is a high-purity, reactive chemical intermediate characterized by its cyclopropane ring and two acid chloride functional groups. This compound is valued for its role as a key building block in the synthesis of complex, stereochemically defined molecules, enabling the introduction of the rigid cyclopropane scaffold. It is primarily sought by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of proprietary drug candidates, particularly those requiring a conformationally constrained cyclopropane moiety to enhance biological activity or metabolic stability.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the cyclopropane structure contributes to the compound's efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organometallic catalysts used in asymmetric synthesis.
• Polymer Modification: Employed to introduce reactive sites or rigid segments into polymer backbones for specialty materials with tailored thermal or mechanical properties.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including ring-opening reactions and cross-coupling methodologies.
• Fine Chemical Production: Integral to the multi-step synthesis of complex flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	1,2-Cyclopropanedicarbonyl Dichloride, 3-Methyl-, (1Alpha,2Beta,3Alpha)- (9Ci)
CAS No.	53957-06-5
Molecular Formula	C7H6Cl2O2
Molecular Weight	193.03 g/mol
Synonyms	3-Methylcyclopropane-1,2-dicarbonyl dichloride; (1R,2S,3R)-3-Methylcyclopropane-1,2-dicarbonyl dichloride; 3-Methyl-1,2-cyclopropanedicarboxylic acid dichloride; 1,2-Cyclopropanedicarbonyl dichloride, 3-methyl-, (1R,2S,3R)-; (1α,2β,3α)-3-Methylcyclopropane-1,2-dicarbonyl Dichloride; 3-Methyl-1,2-cyclopropanedicarboxylic dichloride
EINECS	Contact for details

Quality Control

Our production of 1,2-Cyclopropanedicarbonyl Dichloride, 3-Methyl-, (1Alpha,2Beta,3Alpha)- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including assay by titration, identification by FT-IR and NMR spectroscopy, and impurity profiling by GC or HPLC to ensure high chemical and isomeric purity. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, alcohols, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 97.0%
Isomeric Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.