Description

1,2-Cyclopropanedicarbonyl Dichloride, 1-(1-Methylethyl)-, trans- (9Ci) is a specialized, high-purity organic intermediate featuring a reactive cyclopropane ring and two acid chloride functional groups. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to introduce the unique steric and electronic properties of the cyclopropane moiety into target structures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing constrained cyclopropane rings for enhanced metabolic stability and biological activity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the cyclopropane structure can impart specific activity profiles.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Modification: Employed to introduce functional cross-linking sites or modify the properties of specialty polymers and resins.
• Fine Chemical Production: Acts as a versatile reagent for the preparation of esters, amides, and other derivatives in custom synthesis and scale-up projects.
• Academic and Industrial Research: A valuable tool for methodological development and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	1,2-Cyclopropanedicarbonyl Dichloride, 1-(1-Methylethyl)-, trans- (9Ci)
CAS No.	53922-70-6
Molecular Formula	C9H10Cl2O2
Molecular Weight	221.08 g/mol
Synonyms	trans-1-Isopropyl-1,2-cyclopropanedicarbonyl Dichloride; 1,2-Cyclopropanedicarboxylic Acid, 1-(1-Methylethyl)-, trans-, Dichloride; (1R,2S)-rel-1-(1-Methylethyl)-1,2-cyclopropanedicarbonyl Dichloride; (1S,2R)-rel-1-(1-Methylethyl)-1,2-cyclopropanedicarbonyl Dichloride; trans-1-Isopropylcyclopropane-1,2-dicarbonyl Dichloride; 53922-70-6; 1-(Propan-2-yl)cyclopropane-1,2-dicarbonyl dichloride
EINECS	Contact for details

Quality Control

Our 1,2-Cyclopropanedicarbonyl Dichloride, 1-(1-Methylethyl)-, trans- (9Ci) is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with strong acids and organic solvents; ensure the container is kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.