Description

Bicyclo[4.1.0]Heptane-7-Carbonyl Chloride, (1Alpha,6Alpha,7Beta)- (9Ci) is a specialized bicyclic organic compound featuring a strained cyclopropane ring fused to a cyclohexane ring and a reactive carbonyl chloride functional group. This unique molecular architecture makes it a valuable and versatile building block in advanced organic synthesis, particularly for introducing the rigid bicyclo[4.1.0]heptane scaffold. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, especially those targeting central nervous system (CNS) disorders or requiring specific three-dimensional steric properties.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the bicyclic core can impart unique biological activity and stability.
• Material Science Research: Serves as a precursor for synthesizing specialized polymers or ligands with tailored mechanical or chemical properties.
• Catalyst and Ligand Development: Employed in the preparation of novel chiral catalysts or complexing agents for asymmetric synthesis.
• Academic & Industrial R&D: A critical reagent for methodological studies in organic chemistry, exploring new cyclopropanation or ring-strain utilization reactions.
• Fine Chemical Production: Used in the multi-step synthesis of high-value, complex fragrance or flavor ingredients.

Basic Information

Item	Details
Product Name	Bicyclo[4.1.0]Heptane-7-Carbonyl Chloride, (1Alpha,6Alpha,7Beta)- (9Ci)
CAS No.	53868-60-3
Molecular Formula	C8H11ClO
Molecular Weight	158.62 g/mol
Synonyms	(1α,6α,7β)-Bicyclo[4.1.0]heptane-7-carbonyl chloride; 7-Carbonylchloride-bicyclo[4.1.0]heptane; 1-Norcarenecarbonyl chloride (stereospecific); (1R,6R)-Bicyclo[4.1.0]heptane-7-carbonyl chloride; 7-Chlorocarbonylbicyclo[4.1.0]heptane; Bicyclo[4.1.0]heptane-7-carboxylic acid chloride; Norcarane-7-carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of Bicyclo[4.1.0]Heptane-7-Carbonyl Chloride is produced and analyzed under strict quality management protocols to ensure consistency and purity for sensitive synthetic applications. Our standard grade meets high-purity research specifications, with identity and assay confirmed by advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.