Description

16β-Acetoxy-5,14-Dihydroxy-19-Oxo-5β-Bufa-3,20,22-Trienolide is a high-purity, specialized bufadienolide derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate and reference standard for the synthesis and study of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents. Our supply ensures consistent quality and reliable availability for demanding global R&D and production applications.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic building block for the development of novel cardiac glycosides and other therapeutic agents.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related compounds.
• Biochemical Research: Employed in pharmacological studies to investigate structure-activity relationships (SAR) and mechanism of action.
• Academic Research: Utilized in university and institutional labs for fundamental studies in medicinal chemistry and natural product synthesis.
• Pre-clinical Development: Acts as a starting material or intermediate in the pre-clinical development pipeline for new drug candidates.

Basic Information

Product Name	16β-Acetoxy-5,14-Dihydroxy-19-Oxo-5β-Bufa-3,20,22-Trienolide
CAS No.	53823-13-5
Molecular Formula	C₂₆H₃₄O₈
Molecular Weight	474.55 g/mol
Synonyms	16β-Acetoxy-5,14-dihydroxy-19-oxo-5β-bufa-3,20,22-trienolide; 19-Oxobufalin 16-acetate; Bufadienolide derivative; 5β,14β-Dihydroxy-19-oxo-3β,16β-diacetoxybufa-20,22-dienolide (related structure); Resibufogenin 16-acetate derivative; 16β-Acetoxy-19-oxobufalin; 53823-13-5;
EINECS	Contact for details

Quality Control

Every batch of 16β-Acetoxy-5,14-Dihydroxy-19-Oxo-5β-Bufa-3,20,22-Trienolide is produced and controlled under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Total Impurities	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.