Description

4,4,8-Trimethyl-16-Oxa-18-Nor-5α-Androsta-12-Ene-17-One is a high-purity, synthetic steroid derivative with a modified androstane backbone. This compound serves as a critical advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of specialized steroid-based molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel steroid-based drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new therapeutic candidates.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Biochemical Research: Employed in studies investigating steroid hormone pathways, receptor binding, and metabolic processes.
• Fine Chemical Synthesis: Utilized as a specialized precursor for creating complex, high-value organic molecules in custom synthesis projects.

Basic Information

Product Name	4,4,8-Trimethyl-16-Oxa-18-Nor-5α-Androsta-12-Ene-17-One
CAS No.	53823-04-4
Molecular Formula	C₂₁H₃₂O₂
Molecular Weight	316.48 g/mol
Synonyms	4,4,8-Trimethyl-16-oxa-18-nor-5α-androst-12-en-17-one; 16-Oxa-4,4,8-trimethyl-18-nor-5α-androst-12-en-17-one; 5α-Androst-12-en-17-one, 4,4,8-trimethyl-16-oxa-18-nor-; 4,4,8-Trimethyl-16-oxa-18-norandrost-12-en-17-one; 53823-04-4 (CAS Registry)
EINECS	Contact for details

Quality Control

Our 4,4,8-Trimethyl-16-Oxa-18-Nor-5α-Androsta-12-Ene-17-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.