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9-Arabinofuranosyl-6-Azidopurine CAS NO 53821-43-5


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CAS No.:53821-43-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

9-Arabinofuranosyl-6-Azidopurine is a specialized nucleoside analog featuring an azido functional group at the 6-position of the purine ring. This unique structure makes it a valuable intermediate in the synthesis of novel antiviral and anticancer agents, particularly in the development of nucleoside-based prodrugs and bioconjugates. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on medicinal chemistry and chemical biology.

Application

  • Pharmaceutical Intermediate: A key building block for the synthesis of modified nucleosides with potential antiviral and antitumor activity.
  • Click Chemistry Reagent: The azido group enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and labeling studies.
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new therapeutic candidates.
  • Biochemical Probe Development: Serves as a precursor for creating probes to study enzyme mechanisms and nucleic acid interactions.
  • Antisense Oligonucleotide Synthesis: Potential use in the preparation of modified oligonucleotides for therapeutic applications.
  • Academic & Industrial R&D: Fundamental research tool in chemical biology and drug discovery programs.

Basic Information

Product Name 9-Arabinofuranosyl-6-Azidopurine
CAS No. 53821-43-5
Molecular Formula C10H11N7O4
Molecular Weight 293.24 g/mol
Synonyms 6-Azido-9-β-D-arabinofuranosylpurine; 6-Azido-9-β-D-arabinofuranosyl-9H-purine; 9-β-D-Arabinofuranosyl-6-azidopurine; 6-Azidopurine Arabinoside; 6-N3-Ara-A; Ara-6N3; 6-AzidoaraA
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Quality Control

Our 9-Arabinofuranosyl-6-Azidopurine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep container tightly sealed in a desiccated environment.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥95.0%
Water Content (KF) ≤1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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