Description

2,3,4,6-Tetra-o-Acetyl-α-D-Mannopyranosyl Azide is a key protected glycosyl donor and versatile synthetic intermediate in carbohydrate chemistry. Its primary value lies in enabling the efficient, stereoselective construction of complex oligosaccharides and glycoconjugates through click chemistry and other coupling reactions. This high-purity building block is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel glycomimetics, vaccines, and diagnostic probes.

Application

• Glycoconjugate Synthesis: A critical precursor for the chemoselective synthesis of glycosylated amino acids, peptides, and proteins via Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC).
• Oligosaccharide Assembly: Serves as a key mannosyl donor in block synthesis for constructing complex, biologically relevant oligosaccharide chains.
• Pharmaceutical Intermediates: Used in the research and development of antiviral, anticancer, and anti-inflammatory drug candidates that target carbohydrate-mediated processes.
• Probe and Diagnostic Development: Facilitates the labeling of biomolecules with carbohydrate tags for imaging, biosensing, and diagnostic applications.
• Material Science: Employed in the synthesis of functionalized polymers and surfaces with bioactive carbohydrate motifs.
• Chemical Biology Research: A fundamental tool for studying glycosylation pathways, lectin-carbohydrate interactions, and cell surface engineering.

Basic Information

Product Name	2,3,4,6-Tetra-o-Acetyl-α-D-Mannopyranosyl Azide
CAS No.	53784-29-5
Molecular Formula	C14H19N3O9
Molecular Weight	373.32 g/mol
Synonyms	2,3,4,6-Tetra-O-acetyl-α-D-mannopyranosyl azide; α-D-Mannopyranosyl azide, 2,3,4,6-tetraacetate; 1-Azido-2,3,4,6-tetra-O-acetyl-α-D-mannopyranose; Tetra-O-acetyl-α-D-mannopyranosyl azide; α-Ac4ManN3; Ac4ManαAz; Peracetylated α-mannosyl azide; Mannose(Ac)4-α-azide
EINECS	Contact for details

Quality Control

Our 2,3,4,6-Tetra-o-Acetyl-α-D-Mannopyranosyl Azide is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to rigorous analytical standards, utilizing techniques such as HPLC, NMR, and MS for verification. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere in a freezer (-20°C).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.