Description

(8α)-3',7β-Dihydrocyclopropa[7,8]-5α-Cholestan-3β-Ol is a high-purity, synthetically derived sterol derivative, serving as a critical advanced intermediate in pharmaceutical research and development. Its unique cyclopropane-fused steroidal structure makes it a valuable building block for the synthesis of novel therapeutic agents and reference standards. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of steroidal drugs and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel steroidal pharmaceuticals and active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Biochemical Research: Employed in academic and industrial research to study sterol metabolism, receptor interactions, and structure-activity relationships (SAR).
• Process Chemistry: Serves as a strategic intermediate in complex multi-step organic syntheses for target molecules in medicinal chemistry.
• Fine Chemical Synthesis: Utilized in the production of specialized fine chemicals and advanced materials requiring a defined sterol backbone.

Basic Information

Product Name	(8α)-3',7β-Dihydrocyclopropa[7,8]-5α-Cholestan-3β-Ol
CAS No.	53755-39-8
Molecular Formula	C30H50O
Molecular Weight	426.72 g/mol
Synonyms	3β-Hydroxy-(8α)-3',7β-dihydrocyclopropa[7,8]-5α-cholestane; 5α-Cholestan-3β-ol, (8α)-3',7β-dihydrocyclopropa[7,8]-; Cyclopropa[7,8]-5α-cholestan-3β-ol, (8α)-3',7β-dihydro-; Sterol derivative 53755-39-8; (8α)-3',7β-Dihydrocyclopropa[7,8]cholestan-3β-ol; 53755-39-8
EINECS	Contact for details

Quality Control

Our (8α)-3',7β-Dihydrocyclopropa[7,8]-5α-Cholestan-3β-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and specific tests for residual solvents and related substances. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.