Description

4-Chloro-Pyridine-2-Carbonyl Chloride is a versatile and highly reactive bifunctional organic intermediate. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, due to its ability to introduce both a chloro-substituted pyridine ring and an acid chloride functional group. It is primarily sought by research institutions and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and advanced materials. Its precise reactivity profile makes it an essential building block for modern fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides with pyridine-based active ingredients.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic semiconductors, metal-organic frameworks (MOFs), and functional polymers.
• Custom Synthesis and Contract Manufacturing: A crucial reagent for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	4-Chloro-Pyridine-2-Carbonyl Chloride
CAS No.	53750-66-6
Molecular Formula	C6H3Cl2NO
Molecular Weight	176.00 g/mol
Synonyms	2-Pyridinecarbonyl chloride, 4-chloro-; 4-Chloropicolinoyl chloride; 4-Chloro-2-pyridinecarbonyl chloride; 4-Chloropyridine-2-carboxylic acid chloride; 2-Carbonyl chloride-4-chloropyridine; Picolinoyl chloride, 4-chloro-; 4-Chloro-2-picolinoyl chloride
EINECS	Contact for details

Quality Control

Our 4-Chloro-Pyridine-2-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.