Description

1-Azido-4-Iodobenzene is a versatile bifunctional aromatic compound featuring both an azide and an iodine substituent. This unique structure makes it a critical building block in advanced organic synthesis, particularly for click chemistry and cross-coupling reactions. It is essential for researchers and manufacturers in pharmaceutical development, agrochemical research, and materials science who require reliable, high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates via copper-catalyzed azide-alkyne cycloaddition (CuAAC) and other bioorthogonal reactions.
• Agrochemical Research: Used in developing new active ingredients and tracer molecules for crop protection studies.
• Polymer & Materials Science: Serves as a functional monomer or cross-linking agent for creating advanced polymers, dendrimers, and smart materials.
• Bioconjugation & Labeling: Enables site-specific labeling of biomolecules (proteins, peptides, nucleic acids) for diagnostics and biochemical assays.
• Chemical Probe Synthesis: Employed in medicinal chemistry for creating activity-based probes to study enzyme function and target engagement.
• Ligand & Catalyst Development: Useful precursor for synthesizing specialized ligands and organometallic catalysts used in cross-coupling reactions.

Basic Information

Product Name	1-Azido-4-Iodobenzene
CAS No.	53694-87-4
Molecular Formula	C6H4IN3
Molecular Weight	245.02 g/mol
Synonyms	4-Iodophenyl azide; p-Iodophenyl azide; 4-Azidoiodobenzene; Azidobenzene, 4-iodo-; 1-Iodo-4-azidobenzene; (4-Iodophenyl)azide; p-Azidoiodobenzene; Iodobenzene, 4-azido-
EINECS	Contact for details

Quality Control

Our 1-Azido-4-Iodobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided to guarantee consistency and reliability for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and the presence of an azide functional group, prolonged exposure to light or heat should be avoided. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.