Description

3-Fluorophenacyl Chloride is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in its reactive acyl chloride group and the strategic fluorine substitution, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, including potential CNS agents and anti-inflammatory compounds.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and pesticides with enhanced activity and selectivity.
• Liquid Crystal & OLED Material Production: Used in the synthesis of fluorinated aromatic cores for electronic display and lighting materials.
• Peptide & Protein Modification: Acts as a reagent for specific fluorination or acylation reactions in biochemical research.
• Polymer Chemistry: Monomer or modifier for introducing fluorine atoms into polymer backbones to alter thermal and chemical resistance.
• Dye & Pigment Manufacturing: Intermediate for producing fluorinated chromophores with unique optical properties.

Basic Information

Product Name	3-Fluorophenacyl Chloride
CAS No.	53688-18-9
Molecular Formula	C8H6ClFO
Molecular Weight	172.58 g/mol
Synonyms	2-Chloro-1-(3-fluorophenyl)ethanone; 3-Fluorophenacyl Chloride; 1-(3-Fluorophenyl)-2-chloroethanone; 3'-Fluorophenacyl Chloride; 2-Chloro-3'-fluoroacetophenone; α-Chloro-3-fluoroacetophenone; 3-Fluorophenyl Chloromethyl Ketone
EINECS	Contact for details

Quality Control

Our 3-Fluorophenacyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.