Description

2-Bromo-1-(4-Fluorophenyl)Ethanol is a versatile fluorinated and brominated aromatic alcohol, a key chiral building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of potential drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorophenyl moiety.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials due to its specific halogenated aromatic structure.
• Asymmetric Catalysis & Chiral Ligand Development: Employed as a substrate or a precursor for chiral ligands and catalysts in enantioselective synthesis.
• Academic & Contract Research: Used in university and CRO laboratories for methodological studies in halogenation, fluorination, and asymmetric reduction reactions.
• Fine Chemical Production: Integral in the multi-step synthesis of complex fragrance and flavor molecules requiring specific halogenated intermediates.

Basic Information

Product Name	2-Bromo-1-(4-Fluorophenyl)Ethanol
CAS No.	53617-32-6
Molecular Formula	C8H8BrFO
Molecular Weight	219.05 g/mol
Synonyms	2-Bromo-1-(4-fluorophenyl)ethan-1-ol; 1-(4-Fluorophenyl)-2-bromoethanol; α-Bromo-4-fluorophenethyl alcohol; 4-Fluoro-α-bromophenethyl alcohol; (RS)-2-Bromo-1-(4-fluorophenyl)ethanol; (±)-2-Bromo-1-(4-fluorophenyl)ethanol; 2-Bromo-2-(4-fluorophenyl)ethanol (common misnomer); Br-FPE
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-1-(4-Fluorophenyl)Ethanol is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive in-process and final release testing, including chiral purity analysis where specified, is performed. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Typical 98.0-99.5%)
Chiral Purity (Chiral HPLC)	Specify required enantiomeric excess (ee)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.