Description

12β-Hydroxy-5α-Androstane-3,17-Dione is a high-purity steroid derivative and a key intermediate in the synthesis of complex pharmaceutical compounds. Its specific hydroxylation pattern makes it a valuable building block for research and development in endocrinology and metabolic studies. This compound is primarily utilized by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic research institutions focused on steroid chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or substrate in enzymatic studies related to steroid metabolism and hormone biosynthesis pathways.
• Reference Material: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Academic Research: Employed in university and institutional labs for investigating steroid structure-activity relationships and metabolic transformations.
• Process Development: Used in scaling up and optimizing synthetic routes for novel therapeutic agents within the pharmaceutical industry.

Basic Information

Product Name	12β-Hydroxy-5α-Androstane-3,17-Dione
CAS No.	53608-28-9
Molecular Formula	C19H28O3
Molecular Weight	304.42 g/mol
Synonyms	12β-Hydroxy-5α-androstane-3,17-dione; 5α-Androstane-12β-ol-3,17-dione; 12β-Hydroxyetiocholane-3,17-dione; (5α,12β)-12-Hydroxyandrostane-3,17-dione; 12-Hydroxy-5α-androstanedione; 12β-Hydroxy-5α-androstanedione; 3,17-Dioxo-5α-androstan-12β-ol
EINECS	Contact for details

Quality Control

Our 12β-Hydroxy-5α-Androstane-3,17-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.