Description

3α-Hydroxy-5β-Androstane-12,17-Dione is a high-purity steroid derivative and a key synthetic intermediate in organic chemistry. This compound is valued for its defined stereochemistry and functional groups, which make it a crucial building block for the synthesis of more complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in steroid chemistry, drug discovery, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical starting material or intermediate in the multi-step synthesis of steroid-based active pharmaceutical ingredients (APIs) and drug candidates.
• Research & Development: Used in academic and industrial laboratories for studying steroid metabolism, receptor interactions, and structure-activity relationships (SAR).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in chromatographic analysis (e.g., HPLC, GC).
• Biochemical Synthesis: Employed in the enzymatic or chemical synthesis of specialized steroid hormones and their analogs for biological testing.

Basic Information

Product Name	3α-Hydroxy-5β-Androstane-12,17-Dione
CAS No.	53604-39-0
Molecular Formula	C19H28O3
Molecular Weight	304.43 g/mol
Synonyms	12,17-Dioxo-5β-androstan-3α-ol; 3α-Hydroxy-5β-androstane-12,17-dione; 5β-Androstane-3α-ol-12,17-dione; Etiocholane-3α-ol-12,17-dione; 3α-Hydroxyetiocholane-12,17-dione
EINECS	Contact for details

Quality Control

Our 3α-Hydroxy-5β-Androstane-12,17-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assessment by HPLC, and control of specific impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture, which may affect product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.