Description

2-Furancarbonyl Chloride, Tetrahydro-5-Oxo-, (2R)- (9Ci) is a high-purity chiral building block and acid chloride derivative of significant synthetic utility. This compound is valued for its role as a key intermediate in the synthesis of complex organic molecules, particularly in the pharmaceutical and fine chemical sectors. It is primarily sought by research and development chemists and process engineers involved in the production of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly in stereoselective reactions.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Fine Chemical Production: Serves as a versatile building block for creating complex molecules in custom synthesis and specialty chemical manufacturing.
• Academic & Industrial Research: Employed in methodological development and exploratory chemistry for constructing heterocyclic compounds and natural product analogs.
• Peptide Mimetics & Bioconjugation: The reactive acid chloride group enables its use in coupling reactions to create peptide-like structures or for bioconjugation applications.

Basic Information

Product Name	2-Furancarbonyl Chloride, Tetrahydro-5-Oxo-, (2R)- (9Ci)
CAS No.	53558-94-4
Molecular Formula	C6H7ClO3
Molecular Weight	162.57 g/mol
Synonyms	(2R)-Tetrahydro-5-oxo-2-furancarbonyl chloride; (R)-5-Oxotetrahydrofuran-2-carbonyl chloride; (R)-Tetrahydro-5-oxo-2-furoyl chloride; (2R)-5-Oxotetrahydro-2-furoyl chloride; (R)-γ-Butyrolactone-α-carbonyl chloride; (R)-α-Chlorocarbonyl-γ-butyrolactone; (R)-2-(Chlorocarbonyl)-γ-butyrolactone; (R)-5-Oxo-2-tetrahydrofurancarboxylic acid chloride
EINECS	Contact for details

Quality Control

Our production of 2-Furancarbonyl Chloride, Tetrahydro-5-Oxo-, (2R)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. All materials are subjected to comprehensive analytical testing, including chiral purity assessment by HPLC, identity confirmation by IR and NMR spectroscopy, and impurity profiling. A Certificate of Analysis (COA) detailing specifications such as assay, enantiomeric excess, and related substances is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.