Description

2,3-Dichloro-2-Fluoropropionyl Chloride is a highly reactive bifunctional organofluorine building block, crucial for introducing both fluorine and chlorine substituents into complex molecular architectures. Its value lies in its versatility as an acylating agent and precursor for synthesizing advanced agrochemicals and pharmaceuticals. This compound is essential for R&D chemists and process development teams in the fine chemical, pharmaceutical, and crop protection industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer drug discovery.
• Agrochemical Synthesis: Critical precursor for manufacturing advanced herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Used in the production of fluorinated liquid crystals for high-performance displays.
• Polymer Modification: Serves as a monomer or grafting agent to introduce fluorinated side chains, improving polymer properties like chemical resistance and surface energy.
• Organic Synthesis Reagent: Employed in academic and industrial research labs as a specialized acyl chloride for Friedel-Crafts acylation and other coupling reactions.
• Fluorinated Surfactant Precursor: Intermediate in the manufacture of specialty surfactants and surface treatment agents.

Basic Information

Item	Details
Product Name	2,3-Dichloro-2-Fluoropropionyl Chloride
CAS No.	53510-12-6
Molecular Formula	C3H2Cl3FO
Molecular Weight	179.40 g/mol
Synonyms	2,3-Dichloro-2-fluoropropanoyl chloride; 2-Fluoro-2,3-dichloropropionyl chloride; Propanoyl chloride, 2,3-dichloro-2-fluoro-; 2,3-Dichloro-2-fluoropropionic acid chloride; α-Fluoro-α,β-dichloropropionyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2,3-Dichloro-2-Fluoropropionyl Chloride is manufactured under strict quality management protocols. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from GC, HPLC, and NMR analyses to verify identity, purity, and impurity profiles. Our quality assurance system ensures traceability and compliance with cGMP standards where applicable, meeting the stringent requirements of our global clientele in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place, preferably at 2-8°C for extended stability. This material is hygroscopic (moisture-sensitive) and reacts vigorously with water, strong bases, and alcohols. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.