Description

5-Bromo-2'-Deoxy-6-Ethoxy-5,6-Dihydro-β-Ribofuranosylthymine is a specialized nucleoside analog, a key building block in advanced organic synthesis and pharmaceutical research. This compound is valued for its unique brominated and ethoxy-modified structure, which allows for precise molecular modifications in the development of novel therapeutic agents and biochemical probes. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of antiviral drugs, anticancer compounds, and modified oligonucleotides.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used as a modified nucleoside building block for studying DNA/RNA interactions, enzyme mechanisms, and metabolic pathways.
• Antiviral Drug Development: Serves as a key scaffold in the research and development of compounds targeting viral polymerases and reverse transcriptases.
• Oligonucleotide Synthesis: Employed in the creation of site-specifically modified DNA/RNA strands for diagnostic assays, gene silencing, and probe development.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies to optimize the potency and selectivity of drug candidates.
• Academic Research: A valuable reagent for universities and research institutes exploring novel nucleoside chemistry and its biological applications.

Basic Information

Product Name	5-Bromo-2'-Deoxy-6-Ethoxy-5,6-Dihydro-β-Ribofuranosylthymine
CAS No.	53495-39-9
Molecular Formula	C12H17BrN2O6
Molecular Weight	365.18 g/mol
Synonyms	5-Bromo-2'-deoxy-6-ethoxy-5,6-dihydro-β-D-ribofuranosylthymine; 5-Bromo-6-ethoxy-5,6-dihydro-2'-deoxythymidine; 5-Br-EdThd; 5-Bromo-6-ethoxydihydrothymidine; 2'-Deoxy-5-bromo-6-ethoxy-5,6-dihydrothymidine; 53495-39-9; 5-Bromo-6-ethoxy-5,6-dihydro-2'-deoxyuridine derivative
EINECS	Contact for details

Quality Control

Our 5-Bromo-2'-Deoxy-6-Ethoxy-5,6-Dihydro-β-Ribofuranosylthymine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP (current Good Manufacturing Practice) standards where applicable, and our quality system is designed to meet the rigorous requirements of the pharmaceutical and biotechnology industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.