Description

5-Amino-1-(β-D-Ribofuranosyl)Imidazole-4-Carboxylic Acid Sodium Salt is a key nucleoside intermediate with significant importance in synthetic organic chemistry and pharmaceutical research. Its primary value lies in its role as a versatile building block for the synthesis of complex nucleoside analogs and modified nucleotides. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors, particularly those developing antiviral agents, anticancer therapeutics, and novel biochemical tools.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel nucleoside-based antiviral and anticancer drugs.
• Biochemical Research: Used in the study of nucleotide metabolism, enzyme mechanisms, and as a precursor for labeled compounds in tracer studies.
• Fine Chemical Synthesis: Serves as a specialized starting material for creating modified imidazole nucleosides with tailored biological activity.
• Academic Research: Employed in universities and research institutes for investigating nucleic acid chemistry and developing new synthetic methodologies.
• Precursor for CAR-T & mRNA Technology: Potential use in the synthesis of modified nucleosides for advanced therapeutic platforms, including mRNA vaccines and cell therapies.

Basic Information

Product Name	5-Amino-1-(β-D-Ribofuranosyl)Imidazole-4-Carboxylic Acid Sodium Salt
CAS No.	53459-67-9
Molecular Formula	C9H12N3NaO7
Molecular Weight	297.20 g/mol
Synonyms	5-Amino-1-(β-D-ribofuranosyl)-1H-imidazole-4-carboxylic acid sodium salt; AIR Sodium Salt; 5-Aminoimidazole ribonucleotide sodium salt; 5-Amino-1-β-D-ribofuranosylimidazole-4-carboxylate sodium; 5'-Phosphoribosyl-5-amino-4-imidazolecarboxylic acid sodium salt precursor; CAIR precursor sodium salt; Sodium 5-amino-1-(β-D-ribofuranosyl)-1H-imidazole-4-carboxylate
EINECS	Contact for details

Quality Control

Our 5-Amino-1-(β-D-Ribofuranosyl)Imidazole-4-Carboxylic Acid Sodium Salt is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.