Description

1H-Imidazole-1-Ethanol, Phosphate is a specialized organic phosphate ester derivative of imidazole, serving as a critical intermediate and functional additive in advanced chemical synthesis. Its unique structure, combining a heterocyclic base with a phosphate group, makes it valuable for modifying material properties and facilitating specific chemical reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries seeking to develop new active ingredients or enhance product performance.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or requiring phosphate prodrug strategies.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators where the imidazole moiety imparts biological activity.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce phosphate groups into polymers, enhancing flame retardancy, adhesion, or biocompatibility.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysts for organic transformations.
• Bioconjugation and Prodrug Development: Utilized in bioconjugation chemistry to link active molecules or in designing phosphate-containing prodrugs for improved bioavailability.
• Research & Development: A valuable reagent for academic and industrial R&D in medicinal chemistry, material science, and chemical biology.

Basic Information

Product Name	1H-Imidazole-1-Ethanol, Phosphate
CAS No.	53404-11-8
Molecular Formula	C5H9N2O4P
Molecular Weight	192.11 g/mol
Synonyms	2-(1H-Imidazol-1-yl)ethyl Dihydrogen Phosphate; 1H-Imidazole-1-ethanol, dihydrogen phosphate; Imidazol-1-ylethyl Phosphate; 1-(2-Hydroxyethyl)imidazole Phosphate; 2-Imidazol-1-ylethanol Dihydrogen Phosphate; NSC 163082; 1H-Imidazol-1-yl-ethanol phosphate; Phosphoric Acid Mono-[2-(1H-imidazol-1-yl)-ethyl] Ester
EINECS	Contact for details

Quality Control

Our 1H-Imidazole-1-Ethanol, Phosphate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets exacting specifications for research and industrial use. Certificates of Analysis (COA) are provided with every shipment, detailing all critical quality parameters. We support compliance with relevant frameworks for laboratory and pre-commercial scale applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed after opening to prevent degradation due to moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.