Description

5α-Cholest-2-Ene-2-Methanol CAS NO 53287-18-6 is a high-purity sterol derivative, a key advanced intermediate in the synthesis of complex bioactive molecules. Its unique cholestane-based structure provides a versatile scaffold for pharmaceutical and biochemical research, enabling the development of novel therapeutic agents and analytical standards. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality building blocks for their synthetic pathways.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of steroidal drugs, hormone analogs, and other bioactive compounds.
• Biochemical Research: Used as a precursor or standard in metabolic pathway studies, receptor binding assays, and enzyme inhibition research.
• Fine Chemical Synthesis: Serves as a chiral template or starting material for the production of complex, high-value specialty chemicals.
• Reference Standard: Employed as an analytical standard in HPLC, GC-MS, and NMR for quality control and method development in pharmaceutical analysis.
• Material Science Research: Investigated for the development of novel liquid crystals, polymers, or supramolecular assemblies due to its rigid steroidal backbone.

Basic Information

Product Name	5α-Cholest-2-Ene-2-Methanol
CAS No.	53287-18-6
Molecular Formula	C28H48O
Molecular Weight	400.68 g/mol
Synonyms	2-Methyl-5α-cholest-2-en-2-ol; 5α-Cholest-2-ene-2-methanol; 2-(Hydroxymethyl)-5α-cholest-2-ene; Cholest-2-ene-2-methanol, 5α-; (5α)-Cholest-2-ene-2-methanol; 2-Methylen-5α-cholestan-2-ol (tautomeric form); 5α-Cholest-2-en-2-ylmethanol
EINECS	Contact for details

Quality Control

Our 5α-Cholest-2-Ene-2-Methanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR) and purity assessment by chromatographic techniques (HPLC, GC). A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccant in the storage area.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.